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The repetition of the dose is determined by the nature and force of the response elicited; this response-reveals the actual status of the patient in proportion to the accuracy of the prescription. The speed of the reaction is naturally governed by the course of the individual affection plus the vital reactive power of the individual. Hence, it follows that a quick relief in chronic disease bodes no good, if the remedy has been properly chosen.

No second dose should be given as long as the relief progresses, even though slightly. The amelioration is apt to show itself in the mental state first; the mind becomes more tranquil and the suffering is more easily borne, although its intensity may as yet not be lessened.

In a real cure the symptoms recede from above downward, from within outward and in the reverse order of their coming; all other ways are irregular and open to the suspicion of being mere palliation calculated to destroy the natural symmetry of the manifestations, hence to complicate and render the disease intractible.

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