Action of antibiotic oxacillin on in vitro growth of methicillin-resistant Staphylococcus aureus (MRSA) previously treated with homeopathic medicines

· 2 min read
Homeopathy. 2017 Feb;106(1):27-31. doi: 10.1016/j.homp.2016.10.002. Epub 2016 Dec 3.

Author information

1
ABC Medical School of Santo André, Rua Principe de Gales, 821 Santo André, Brazil. Electronic address: [email protected]
2    ABC Medical School of Santo André, Rua Principe de Gales, 821     Santo André, Brazil. Electronic address: [email protected]
3   ABC Medical School of Santo André, Rua Principe de Gales, 821 Santo André, Brazil. Electronic address: [email protected]
4  ABC Medical School of Santo André, Rua Principe de Gales, 821 Santo André, Brazil. Electronic address: [email protected]
5  Department of Biotechnology and Pharmacy, Anhanguera University of São Paulo, São Paulo, Brazil. Electronic address: [email protected]
6 Outpatient Clinic, São Paulo Medical Association, Rua Diogo de Faria 839, São Paulo, SP, Brazil. Electronic address: [email protected]

Abstract

BACKGROUND:

Resistance to antibiotics is a major public health concern worldwide. New treatment options are needed and homeopathy is one such option. We sought to assess the effect of the homeopathic medicine Belladonna (Bell) and a nosode (biotherapy) prepared from a multi-drug resistant bacterial species, methicillin-resistant Staphylococcus aureus (MRSA), on the same bacterium.

METHODS:

Bell and MRSA nosode were prepared in 6cH and 30cH potencies in 30% alcohol and sterile water, according to the Brazilian Homeopathic Pharmacopeia and tested on MRSA National Collection of Type Cultures (NCTC) 10442. We assessed in vitro bacterial growth, deoxyribonuclease (DNAase) and hemolysin activity, and in vitro bacterial growth in combination with oxacillin (minimum inhibitory concentration – MIC). All values were compared to control: 30% alcohol and water.

RESULTS:

In vitro growth of MRSA was statistically significantly inhibited in the presence of Bell and nosode 6cH and 30cH compared to controls (p < 0.0001); and with combination of Bell or nosode 6cH and 30cH and oxacillin (p < 0.001). Bell 30cH and nosode 6cH and 30cH significantly decreased bacterial DNAse production (p < 0.001) and reduced red blood cell lysis.

CONCLUSIONS:

Cultures of MRSA treated with Belladonna or MRSA nosode exhibited reduced growth in vitro, reduced enzymatic activity and became more vulnerable to the action of the antibiotic oxacillin. Further studies are needed on the biomolecular basis of these effects.

KEYWORDS:

Belladonna; DNase; Hemolysin; In vitro growth; MRSA; Nosode; Oxacillin

Related Articles

Homeopathic treatment of mild traumatic brain injury

A randomized, double-blind, placebo-controlled clinical trial. Abstract BACKGROUND: Mild traumatic brain injury (MTBI) affects 750,000 persons in the United

· 1 min read

Large-scale application of highly-diluted bacteria for Leptospirosis epidemic control.

Homeopathy. 2010 Jul;99(3):156-66. doi: 10.1016/j.homp.2010.05.009. Bracho G1, Varela E, Fernández R,

· 1 min read

Vitiligo Cure by Homoeopathy

Abstract Vitiligo known as leucoderma is a relatively common skin disorder, in which white spots or patches appear on the

· 1 min read

Natrum muriaticum, the amazing story of Dao by Micheline Deltombe

Summary Dr. Micheline Deltombe-Kopp, founder of the Association of French Speaking Homeopath Paediatricians, tells the story of an adopted child

· 1 min read

Arnica montana L. – A plant of healing

First published: 11 April 2017 Full publication history DOI: 10.1111/jphp.12724  View/save citation Cited by (CrossRef): 0

· 1 min read

A Case Well Taken: Using the Homeopathy Questionnaire Model as an Intake Tool for Psychotherapy

CASE TAKING My experience of homeopathy included treatment to assist me in finding relief from grief and depression stemming from

· 1 min read